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Since the greatest advantage of the central impression cylinder press is its ability to hold excellent register, it has become the mainstay of the converting industry. Also, with graphic designs becoming more complicated and the demand for process printing remaining steady, the positive register ability of the CI press makes it suitable for all types of substrates. The most common press in use today is still the six-color central impression press, although this is being superceded by the eight-color CI press. Even ten-color CI presses are being now built.

Impression cylinders of various diameters have been used. At first, four-color presses were the most common, and they generally used 30 or 36-diameter impression cylinders. To get better speed and allow room for interstation drying, impression cylinders up to 60" were used for four-color presses. The first six-color central impression cylinder presses used 83" diameter cylinders. The latest eight-color central impression presses have cylinders up to 94" in diameter. As drying techniques have improved and the distance required for drying between colors has decreased, smaller impression cylinders have come back into use. The most common eight-color single impression cylinder press today has an 89" (2.26 meter) diameter cylinder.

Thanks to advances in between-color drying, the adage that "larger cylinder presses usually offer higher speeds" no longer applies. In general, however, it is still possible to get longer printing repeat lengths on the larger impression cylinder presses than those of smaller design.

The central impression press has found limited use when it comes to printing both sides of a web during one pass through the press, most commonly in tubular film printing.